A new proteomic instrument: The Olink Signature Q100
Olink started its commercial laboratory in the Boston area in 2016, based upon the Proximity Extension Assay technology and method published in a 2014 PLoS One paper entitled “Homogenous 96-plex PEA...
View ArticleSingle-cell interaction technology from Scribe Biosciences
Madrigal et al PNAS Feb 2022 Figure 2 Way back in 2009 I remember the first time my sales manager at RainDance Technologies presented their core technology to a sophisticated group at the US National...
View ArticleThe UK Biobank – a veritable fountain of discovery
The UK Biobank (abbreviated UKB or UKBB) began in 2006 as a long-term study to investigate the ‘respective contributions of genetic predisposition and environmental exposure (including nutrition,...
View ArticleCombining genomics with proteomics opens a new era of discovery
That summer day in 2000 was a memorable one: President Bill Clinton with Prime Minister Tony Blair, then-NHGRI Director Francis Collins, and then-CEO of Celera Craig Venter announcing the draft map of...
View ArticleElement Biosciences AVITI™ Sequencing System
For a technology that started in 2005 with the first 454 / Roche FLX next-generation sequencing (NGS) platform, followed in 2007 with the Solexa / Illumina Genome Analyzer, and then in 2010 with the...
View ArticleA 2022 NGS Cost and Throughput Comparison
After spending some time in Los Angeles this week visiting a few existing and potential customers for Olink Proteomics, I was able to talk with a few friends about their perspective at this particular...
View ArticleDiscovery of a novel mechanism unique to severe COVID leads to a potential...
A few weeks ago you read about the depth of the UK BioBank which I called a ‘veritable fountain of discovery’ along with five interesting results and hints of what’s to come in the future. Combining...
View ArticleProteomics in Proximity: Co-Hosting a New Podcast
Do you listen to podcasts? Would you be interested in learning about how Olink Proteomics’ technology is applied in biomarker discovery, drug discovery, proteogenomics, and routine research into...
View ArticleSilent Valley Consulting – open for business
Several years ago during the publishing of the book about COVID-19 diagnostics, therapeutics and vaccines (“Chaos to Cure”), I registered a business with the state of Maryland called Silent Valley...
View ArticleObservations about Helicos, a single molecule sequencer from 2008
Take a look at the latest blog post from Dale Yuzuki, published on the Silent Valley Consulting website, about a technology from 2008 to 2011 that was the world’s first “true single molecule...
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